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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCH2
All Species:
14.55
Human Site:
S922
Identified Species:
32
UniProt:
O75038
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75038
NP_055453.2
1416
154668
S922
P
P
A
R
P
S
V
S
Q
R
I
L
R
R
T
Chimpanzee
Pan troglodytes
XP_001149239
1685
188441
G906
Y
V
R
K
R
S
I
G
D
R
I
L
R
R
T
Rhesus Macaque
Macaca mulatta
XP_001085424
1423
155915
S929
P
L
A
R
P
S
V
S
Q
R
L
L
R
R
T
Dog
Lupus familis
XP_546733
1387
151432
S906
P
L
P
R
P
S
V
S
Q
R
L
L
R
R
T
Cat
Felis silvestris
Mouse
Mus musculus
A2AP18
1501
164279
S1003
P
L
P
R
P
S
V
S
Q
R
L
L
R
R
T
Rat
Rattus norvegicus
Q62688
1096
122754
S646
F
L
S
R
V
Y
P
S
A
M
R
I
D
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q2VRL0
637
72514
L187
Q
L
I
G
P
S
D
L
N
G
Y
I
S
A
L
Frog
Xenopus laevis
Q32NH8
758
87399
Y308
I
S
S
S
H
N
T
Y
L
M
E
D
Q
I
R
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
K334
S
H
N
T
Y
L
T
K
D
Q
V
T
S
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25455
1318
146373
A868
D
L
S
N
F
A
E
A
L
A
N
P
I
K
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783611
2724
302530
H1130
V
P
L
N
E
I
I
H
I
L
R
L
G
I
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.4
94
78.7
N.A.
77.2
21.2
N.A.
N.A.
21.2
24.7
24.5
N.A.
24.2
N.A.
N.A.
26.4
Protein Similarity:
100
59.9
95.4
82.9
N.A.
81.6
36.7
N.A.
N.A.
30.7
35.3
35
N.A.
40.3
N.A.
N.A.
35.7
P-Site Identity:
100
46.6
86.6
80
N.A.
80
13.3
N.A.
N.A.
13.3
0
0
N.A.
0
N.A.
N.A.
13.3
P-Site Similarity:
100
60
93.3
86.6
N.A.
86.6
33.3
N.A.
N.A.
20
20
20
N.A.
26.6
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
19
0
0
10
0
10
10
10
0
0
0
19
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
10
0
19
0
0
10
10
0
0
% D
% Glu:
0
0
0
0
10
0
10
0
0
0
10
0
0
0
0
% E
% Phe:
10
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
0
0
10
0
10
0
0
10
0
0
% G
% His:
0
10
0
0
10
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
10
0
10
0
0
10
19
0
10
0
19
19
10
19
0
% I
% Lys:
0
0
0
10
0
0
0
10
0
0
0
0
0
10
0
% K
% Leu:
0
55
10
0
0
10
0
10
19
10
28
55
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
19
0
0
0
0
0
% M
% Asn:
0
0
10
19
0
10
0
0
10
0
10
0
0
0
0
% N
% Pro:
37
19
19
0
46
0
10
0
0
0
0
10
0
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
37
10
0
0
10
0
0
% Q
% Arg:
0
0
10
46
10
0
0
0
0
46
19
0
46
46
10
% R
% Ser:
10
10
28
10
0
55
0
46
0
0
0
0
19
10
28
% S
% Thr:
0
0
0
10
0
0
19
0
0
0
0
10
0
0
46
% T
% Val:
10
10
0
0
10
0
37
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
10
10
0
10
0
0
10
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _